Sunday, January 26, 2020

Quinapril HCl (QUI) and Hydrochlorthiazide (HCTZ) Literature

Quinapril HCl (QUI) and Hydrochlorthiazide (HCTZ) Literature LITERATURE REVIEW Reema jaiswal, Pinak patel et al., (2013) developed and reported a new simple, sensitive, rapid, accurate, precise and economical RP-HPLC method for the simultaneous determination of Quinapril HCl (QUI) and Hydrochlorthiazide (HCTZ) in their combined pharmaceutical dosage form using potassium Dihydrogen Phosphate buffer (pH 4.0 adjusted with Ortho Phosphoric acid):Acetonitrile(70:30v/v) mobile phase, and C18 column ODS(100 mm x 4.6 mm,3.0ÃŽ ¼ particle size) as stationary phase with detection wavelength of 215 nm. Linearity was obtained in the concentration range of 5-25 ÃŽ ¼g/ml for both the drugs. The % recoveries of the both the drugs were found to be 99.50 – 101.50 % and 99.00 101.06%respectively.The LOD were found to be 0.014ÃŽ ¼g/ml and 0.013ÃŽ ¼g/ml at 215 nm for QUI and HCTZ respectively. Methods were statistically validated for Accuracy, precision, specificity, LOQ, and robustness according to ICH guidelines and can be used for analysis of combined dosage form. Serkan ALTUNSOY, Burà §in BOZAL-PALABIYIK, Bengi USLU et al., (2013) developed and reported a RP-HPLC method for the simultaneous determination of quinapril (QNP) and hydrochlorothiazide (HCZ) in pharmaceutical dosage forms. In this method quinapril, hydrochlorothiazide and perindopril (internal standard) were separated using a reversed phase column (Hichrom C18; 250Ãâ€"4.6 mm i.d.; 10 ÃŽ ¼m) with acetonitrile: potassium dihydrogen phosphate (at pH 2.5; 0.067 M) (40:60 v/v) as a mobile phase using UV detector at 211 nm and flow rate was 1.0 ml/min. The retention times for quinapril, hydrochlorothiazide and perindoprile were 4.391, 3.237 and 3.931 min, respectively. Linearity was obtained in the concentration range of 2-30 ÃŽ ¼g/mL for QNP and 1.25-18.75 ÃŽ ¼g/mL for HCZ. The proposed method has been fully validated and method is simple, rapid and suitable for quality control (QC) applications. Khan SA, Kulkarni SS, Biyani KR and Khan BA et al., (2013) developed and reported a simple, sensitive, accurate and reproducible method for simultaneous estimation of Quinapril and Hydrochlorthiazide by the Simultaneous equation method, using methanol as solvent. The two wavelengths 257 nm ÃŽ »max of Quinapril Hydrochloride (QNA-H) and 271 nm ÃŽ »max of Hydrochlorothiazide (HCTZ) were selected for the formation of Simultaneous equations. The two drugs follow Beer-Lambert’s law over the concentration range of 5- 30 ÃŽ ¼g/ml of QNA-H and 2.5 – 15 ÃŽ ¼g/ml of HCTZ. Recovery study was performed to confirm the accuracy of the method. The recovery of the Quinapril Hydrochloride and Hydrochlorothiazide were found near to 100 %. The Results were found to satisfactory and reproducible. The methods were validated as per ICH guidelines. Reema Jaiswal, Pinak patel et al., (2013) developed and reported a new economical Derivative Spectrophotometric method for the simultaneous determination of Quinapril HCl (QUI) and Hydrochlorthiazide (HCTZ) in their combined pharmaceutical dosage form was developed and the absorbance of the solutions were measured at 242.45 nm (ÃŽ »1), and 257.17 nm (ÃŽ »2) for the estimation of both the drugs. The linearity was obtained in the concentration range of 80-240 ÃŽ ¼g/ml for QUI and 10-50 ÃŽ ¼g/ml for HCTZ The mean recovery was 99.93 – 100.33 % and 99.06- 101.25% for QUI and HCTZ respectively. The results of analysis have been validated statistically as per ICH guidelines. Gandhimathi and Ravi et al., (2013) developed and reported an ion-pair HPLC method has been developed and validated for the estimation of quinapril and hydrochlorothiazide simultaneously in combined dosage form. The mobile phase used was a mixture of 0.1% v/v triethylamine (pH 3.5), containing 1M of hexane sulphonic acid: acetonitrile (30:70% v/v). The detection was carried out on photo diode array detector at 220 nm. The proposed method can be successfully used to determine the drug contents of marketed formulation. Girija B. Bhavar, V.A Chatpalliwar, D.D. Patil and S.J. Surana et al., (2008) developed and reported HPTLC method for simultaneous estimation of Quinapril and Hydrochlorthiazide in pharmaceutical formulations. The drugs were separated on silica gel 60 F254 plates using suitable combination of solvents as mobile phase. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of methods. Mariusz Stolarczyk, Anna Maalanka, Anna Apola et al., (2013) developed spectrophotometric and chromatographic-densitometric methods for determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical preparations. The measurements were carried out at ÃŽ » = 224.0 nm for quinapril, ÃŽ » = 261.0 nm for hydrochlorothiazide and ÃŽ » = 270.0 nm for losartan when the derivative spectrophotometry was applied and ÃŽ » = 317.0 nm when zero order spectrophotometry was applied for the determination of hydrochlorothiazide. In chromatographic-densitometric studies high performance thin layer chromatography (HPTLC) plates were used as stationary phase and a mixture of solvents n-butanol : acetic acid : water (15 : 5 : 1, v/v/v) as mobile phase. Under the established conditions good resolution of examined constituents was obtained. Retardation factor for quinapril hydrochloride was Rf ~ 0.70, for losartan potassium Rf ~ 0.85 and for hydrochlorothiazide Rf ~ 0. 78. The developed methods are characterized by high sensitivity and accuracy. For quantitative analysis, densitometric measurements were carried out at ÃŽ » = 218.0 nm for quinapril, ÃŽ » = 275.0 nm for hydrochlorothiazide and ÃŽ » = 232.0 nm for losartan. Kunal Makwana, Reena V Dhamecha, Nilesh Pandya et al., (2011) developed a rugged and economic method for the estimation of quinapril and its metabolite in human serum by lcms/ms detection for clinical trials. Ramipril was used as internal standard for quantitation of Quinapril, and it metabolite from human serum. Linear regression with 1/X2 weighting was performed to determine the concentration of the drug from serum . A common solid phase extraction procedure for the isolation of drug and its metabolite was developed from serum samples. The samples were analyzed on API 3200 Triple quadrapole mass spectrometer using Chromolith, RPà ¢Ã¢â€š ¬Ã‚ 18e column in atmospheric pressure electro spray ionization. The mobile phase composition was an isocratic mixture of 0.01% Ammonia in water: acetonitrile (30:70 %v/v). The method was validated over a linear range of 10 – 1000 ng/mL and the limit of quantification was 10 ng/mL. Recoveries were observed above 70% for all the three analyt es. The storage stability of Quality control samples was investigated under various conditions Wagh, Hapse. S. A.; Kadaskar, V. S.; Dokhe, P. T.; Shirsath, A. S. et al., (2012) developed a method for the estimation of hydrochlorothiazide in tablet dosage form. This analytical method developed for the estimation of hydrochlorothiazide in bulk fluids showed maximum absorbance at ÃŽ »max of 272 nm in distilled water and in 0.01N NAOH between 200 nm and 400 nm of UV scan. The method developed was validated for accuracy, linearity, limit of detection and limit of quantitation studies. The above analytical parameters indicated that the developed UV Spectrophotometric method of hydrochlorothiazide was simple, accurate and reproducible. Neela M Bhatia, Rituraj B Desai and Swapnil D Jadhav et al., (2012) reported a simple spectrophotometric method development for simultaneous estimation of Losartan Potassium (LOS) and Hydrochlorothiazide (HCT) in two component tablet formulation. The method employed is a first order derivative spectroscopy. The wavelengths used for detection were 257 nm for LOS and 243 nm for HCT. Linearity was observed in the range of 10-90 ÃŽ ¼g/ml for LOS and 2.5-22.5 ÃŽ ¼g/ml for HCT. The recovery studies confirmed accuracy of proposed method and low values of standard deviation confirmed precision of method. The method is validated as per ICH guidelines. R. K. Patel, J. B. Patel et al., (2011) developed accurate, precise and sensitive UV spectrophotometric method for the determination of Nebivolol Hcl (NEB-H) and Hydrochlorothiazide (HCTZ) in bulk as well as in the pharmaceutical formulation. Calibration curves were linear in range of 10-80 ÃŽ ¼g/mL (r2=0.999) and 2-16 ÃŽ ¼g/mL (r2=0.998) at ÃŽ »max of 281 and 271nm for Nebivolol HCl and Hydrochlorothiazide respectively. The method was validated statistically. Monika L. Jadhav, Manoj V. Girase, Shripad K. Tidme et al., (2014) developed two UV spectrophotometric methods and validated for simultaneous estimation of valsartan and hydrochlorothiazide in a tablet dosage form. The first method employed solving of simultaneous equations based on the measurement of absorbance at two wavelengths, 249.4 nm and 272.6 nm, à °Ã‚ Ã…“† max for valsartan and hydrochlorothiazide, respectively. The second method was absorbance ratio method, which involves formation of Q-absorbance equation at 258.4nm (isoabsorptive point) and also at 272.6nm (à °Ã‚ Ã…“† max of hydrochlorothiazide). The methods were found to be linear between the range of 5–30 à °Ã‚ Ã…“†¡g/ml for valsartan and 4–24 à °Ã‚ Ã…“†¡g/ml for hydrochlorothiazide using 0.1N NaOH as solvent. The mean percentage recovery was found to be 100.20% and 100.19% for the simultaneous equation method and 98.56% and 97.96% for the absorbance ratio method, for va lsartan and hydrochlorothiazide, respectively, at three different levels of standard additions. The precision (intraday, interday) of methods was found within limits (RSD Shilpa Korti, Channabasavaraj KP, Somashekar PL et al., (2014) reported a new, simple (RP-HPLC) method and validated for simultaneous estimation of Moxonidine(MOX) and Hydrochlorothiazide (HCTZ) in bulk drug and tablet dosage forms. The separation was achieved by using C8 Phenomenex Luna (250 x 4.6mm, 5ÃŽ ¼m) column with a mobile phase acetonitrile and formic acid solution (0.2%v/v) in the ratio 50:50 by using flow rate of 0.8 ml/min and detection wavelength at 245 nm. The retention times of MOX and HCTZ were found to be 3.0 and 4.8 min and the calibration curves were linear (r2=0.999) over a concentration range from 1-35ÃŽ ¼g/mL for MOX and HCTZ respectively. Limit of detection (LOD) and Limit of quantitation (LOQ) were 0.08ÃŽ ¼g/mL and 0.1ÃŽ ¼g/mL for MOX and 0.2ÃŽ ¼g/mL and 0.4ÃŽ ¼g/mL for HCTZ respectively. The developed method was validated as per ICH guidelines and the results were found to be within the limits. So it can be used for the routine quality control of MOX and HCTZ in bulk sample and tablet dosage forms. Vidhya K. Bhusari, Sunil R. Dhaneshwar et al., (2011) reported a new and accurate HPTLC method for simultaneous estimation of Atenolol, Hydrochlorothiazide and Amlodipine Besylate as the bulk drug and in tablet dosage forms by using aluminum plates precoated with silica gel 60 F254 as the stationary phase and chloroform: methanol: acetic acid (8: 2: 0.2 v/v/v) as mobile phase. Densitometric evaluation of the separated zones was performed at 232 nm. The three drugs were satisfactorily resolved with RF values 0.22  ± 0.02 and 0.36  ± 0.02, 0.55  ± 0.02 for Atenolol, Hydrochlorothiazide and Amlodipine Besylate, respectively. The accuracy and reliability of the method was assessed by evaluation of linearity (100-600 ng/spot for Atenolol, Hydrochlorothiazide and Amlodipine Besylate), precision (intra-day % RSD was 0.37–1.19 and inter-day % RSD was 0.69–1.11 for Atenolol, intra-day % RSD was 0.49–1.16 and inter-day % RSD was 0.50–1.23 for Hydrochlorothiazi de and intra-day % RSD was 0.59–0.84 and inter-day % RSD was 0.60–0.91 for Amlodipine Besylate), accuracy (99.93  ± 0.43 for Atenolol, 99.92  ± 0.72 for Hydrochlorothiazide and 99.87  ± 0.63 for Amlodipine Besylate), and specificity in accordance with ICH guidelines. Havaldar Freddy H and Vairal Dharmendra L et al., (2010) developed a simple, specific (RP-HPLC) method and validated for the determination of atenolol, hydrochlorothiazide, losartan and valsartan. Separation was achieved with a Nucleodur 100 C–18 column having 250 x 4.6mm i.d. with 5ÃŽ ¼m particle size and potassium dihydrogen phosphate buffer adjusted to pH 3.0 using diluted ortho phosphoric acid and acetonitrile (50:50 v à ¢Ã‹â€ Ã¢â‚¬ ¢ v) at flow rate of 1.0ml/min using UV detection at 210nm. The retention time of atenolol, hydrochlorothiazide, losartan and valsartan was about 1.99min, 2.90min, 5.92min and 9.42min respectively. The proposed method was validated and successfully used for estimation of atenolol, hydrochlorothiazide, losartan and valsartan in the pharmaceutical dosage form.

Saturday, January 18, 2020

Ch01 Organizations and Organization Theory

Chapter 1: Organizations and Organization Theory Current Challenges of Organizations †¢ Globalization o Markets, technologies, and organizations are becoming increasingly interconnected †¢ Ethics and social responsibility o The list of execs and major corporations involved in financial and ethical scandals continues to grow †¢ Speed of responsiveness o Globalization and advancing technology has accelerated the pace at which organizations in all industries must roll out new products and services to stay competitive †¢ The digital workplace In today’s workplace, many employees perform much of their work on computers and may work in virtual teams, connected electronically to colleagues around the world †¢ Diversity o By 2050, it is estimated that 85% of entrants into the workforce will be women and people of colour What Is an Organization? Organizations: social entities that are goal-directed, are designed as deliberately structured and coordinated activi ty system, and are linked to the external environment Types of Organizations †¢ Multinational corporations †¢ Small, family-owned shops †¢ For-profit versus non-profit organizationsOrganizations exist to do the following: 1. Bring together resources to achieve desired goals and outcomes 2. Produce goods and services efficiently 3. Facilitate innovation 4. Use modern manufacturing and information technologies 5. Adapt to influence a changing environment 6. Create value for owners, customers, and employees 7. Accommodate ongoing challenges of diversity, ethics, and the motivation and coordination of employees Perspectives on Organizations Closed System †¢ A system that is autonomous, enclosed, and not dependent on its environment †¢ Don’t truly exist today Early management concepts such as scientific management, leadership style, and industrial engineering were closed-system approaches Open System †¢ A system that must interact with the environment to survive †¢ It both consumes resources and exports resources to the environment, and must continually adapt to the environment An Open System and its Subsystems [pic] Organization Configuration †¢ Technical core o Includes people who do the basic work of the organization o The primary transformation of inputs to outputs occurs here o Includes production department, teachers and classes, medical activities in hospitals, etc. Technical Support o Helps the organization adapt to the environment o Technical support employees such as engineers and researchers scan the environment for problems, opportunities, and technological developments o Responsible for creating innovations in the technical core †¢ Administrative Support o Responsible for the smooth operation and upkeep of the organization, including its physical and human elements o Includes HR activities like recruiting and hiring, making compensation/benefit plans, employee training, etc. †¢ Management A disti nct subsystem responsible for directing and coordinating other parts of the organization o Top management provides direction, strategy, goals, and policies for the entire organization or major divisions o Middle management is responsible for implementation and coordination at the departmental level [pic] Dimensions of Organization Design Structural Dimensions 1. Formalization ? Pertains to the amount of written documentation in the organization, including procedures, job descriptions, regulations, and policy manuals, describing behaviour and activities ?A large state university would be high on formulization and a small, family-owned business would be low on formulization 2. Specialization ? The degree to which organizational tasks are subdivided into separate jobs 3. Hierarchy of authority ? Describes who reports to whom and the span of control for each manager ? The hierarchy is related to span of control (the number of employees reporting to a supervisor), and when the span is na rrow, the hierarchy is tall, and vice versa 4. Centralization ? Refers to the hierarchical level that has authority to make a decision ?When decision making is kept at the top level, the organization is centralized ? When decisions are delegated to lower organizational levels, it is decentralized 5. Professionalism ? The level of formal education and training of employees ? It’s considered high when employees require long periods of training ? Professionalism is measured as the average number of years of education of employees 6. Personnel ratios ? Refer to the development of people to various functions and departments ?Includes the administrative ratio, the clerical ratio, the professional staff ratio, and the ratio of indirect to direct labour employees ? A personnel ratio is measured by dividing the number of employees in a classification by the total number of organizational employees [pic] Contextual Dimensions 1. Size ? The organization’s magnitute as reflected i n the number of people in the organization ? Because organization’s are social systems, it’s typically measured by # of employees 2. Organizational technology ? Refers to the tools, techniques, and actions used to transform inputs into outputs ?It concerns how the organization actually produces the products and services and includes things such as flexible manufacturing, advanced info systems, and the Internet 3. Environment ? Includes all elements outside the boundary of the organization ? Key elements include the industry, government, customers, suppliers, and the financial community 4. Goals and Strategies ? Define the purpose and competitive techniques that set it apart from other organizations ? Goals are written down as an enduring statement of company intent ?A strategy is the plan of action that describes resource allocation and activities for dealing with the environment and for reaching the organization’s goals 5. Culture ? The underlying set of key va lues, beliefs, understandings, and norms shared by employees ? These values may pertain to ethical behaviour, commitment to employees, efficiency, or customer service Performance and Effectiveness Outcomes †¢ Managers adjust structural and contextual dimensions and organizational subsystems to most efficiently and effectively transform inputs into outputs nd provide value †¢ Efficiency refers to the amount of resources used to achieve the organization’s goals, and it is based on the quantity of inputs necessary to produce a given level of output †¢ Effectiveness is the degree to which an organization achieves its goals †¢ Stakeholder is any group within or outside an organization that has a stake in the organization’s performance †¢ Stakeholder approach assesses the satisfaction of stakeholders as an indicator of the organization’s performance (also called constituency approach) †¢ Major stakeholders and what they expect: Owners/sto ckholders: financial return o Employees: satisfaction, pay, supervision o Customers: high-quality goods/services, service, value o Creditors: creditworthiness, fiscal responsibility o Management: efficiency, effectiveness o Government: obedience to laws and regulations, fair competition o Union: worker pay, benefits Community: good corporate citizen, contribution to community affairs o Suppliers: satisfactory transactions, revenue from purchases The Evolution of Organization Theory and Design Historical Perspectives †¢ Efficiency is everything o Frederick Winslow Taylor developed scientific management, which claims decisions about organization and job design should be based on precise, scientific procedures †¢ How to get organized Administrative principles focuses on the total organization (looks at the organization as a whole) o For example, Henri Fayol proposed 14 principles of management, such as â€Å"each subordinate receives orders from only one superior† and â€Å"similar activities in an organization should be grouped together under one manager† o These gave organizations fundamental new ideas for estabilishing high productivity and increasing prosperity o Administrative principles contributed to the development of bureaucratic organizations, which emphasized designing and managing organizations on an impersonal, rational basis through such elements as clearly defined authority and responsibility, formal recordkeeping, and uniform application of stand rules †¢ People o Hawthorn Studies are a series of experiments on worker productivity that began in 1924 o It attributed employees’ increased output to managers’ better treatment of them during the study †¢ Environment Many problems occur when all organizations are treated similar, which is the case with scientific management o Structures and systems that work in the retail division will not be appropriate for the manufacturing division o Consistency means t hat one thing depends on other things, and for organizations to be effective, there must be a â€Å"goodness of fit† between their structure and the conditions in their external environment o Some organizations experience a certain environment, use a routine technology, and desire efficiency, and in this case, bureaucratic controls would be appropriate o But today, almost all organizations operate in a highly uncertain environment Contemporary Organizational Design Today’s organizations and managers are shifting from a mindset based on mechanical systems to one based on natural and biological systems †¢ Chaos theory suggests that relationships in complex, adaptive systems – including organizations – are made up of numerous interconnections that create unintended effects and render the environment unpredictable †¢ Many organizations are shifting from strict vertical hierarchies to flexible, decentralized structures that emphasize horizontal colla boration, widespread info sharing, and adaptability †¢ Learning organization is an organization in which everyone is engaged in identifying and solving problems, enabling the organization to continuously experiment, improve, and increase its capability Efficient Performance versus the Learning Organization †¢ From vertical to horizontal structure †¢ From routine tasks to empowered tasks †¢ From formal control systems to shared information †¢ From competitive to collaborative strategy †¢ From rigid to adaptive culture ———————– Transformation Process Environment Raw Materials People Information resources Financial resources Input Subsystems Boundary Spanning Production, Maintenance, Adaptation, Management Boundary Spanning Products and Services Output Top Management

Thursday, January 9, 2020

Ielts Essay Writing Band 9 Samples - the Conspiracy

Ielts Essay Writing Band 9 Samples - the Conspiracy I will explain to you how to analyse the undertaking, plan this, and write it to a band nine level. Let's take these respective points and learn to compose a letter that provides you a band 9 score. As soon as you are finished you can leave a line and get started writing after the left line from the extremely left of the webpage. Do you want to know how to boost your ielts band score. Life, Death, and Ielts Essay Writing Band 9 Samples Some claim they reduce costs and are better for the surroundings, others feel they are a severe threat to energy security. There are several different forms of questions that involve various practices and have various challenges you will need to be ready for them all. Folks need to be careful to underestimate the worth and power of knowledge. Go over the benefits of both methods and provide your own opinion. Type 2 questions are like the brief answer questions in they will inform you to c ompose your answers in NO MORE THAN THREE WORDS. Naturally, it is necessary to do practice tests at home, but you also will need to concentrate on question types. The remainder of the questions ought to be again quite simple handle for good language users. Every test-taker dreams of becoming inside details on the latest test questions. Academic Task 1 lets you demonstrate you can understand visual data and importantly, that you could describe it into a manner that demonstrates this understanding. General Task 1 questions are composed of 3 unique pieces. Please be aware this report is a lot shorter than normal because there were not any recommendations for improvement. Finally, some artists might be fortunate enough to get donations from wealthy individuals. Hence, it's said, marry for money is right in a point. A big disadvantage of an admission fee is the chance of cutting back the quantity of visitors. Spending a great deal of time looking for ielts info. Top Ielts Ess ay Writing Band 9 Samples Choices Consequently, they can share one another's sadness, happiness to overcome any difficulties in their day-to-day lives. However, I think that marriage should involve a combo of both love and money. At length, the most important explanation is that studying family history is a significant tool in maintaining good physical wellness. Certainly, money is a significant role in our lives. Certainly, it plays an important part in our lives. It's hard for any persons to accept a partner who doesn't have money or no less than a job to care for their upcoming family. It's hard for any persons to accept a partner that does not have money or no less than a job to manage future family. There are several smart scientists who don't have the funds to acquire important info to finish their research. Exhibits are among the few cultural activities they may enjoy at no cost. The Battle Over Ielts Essay Writing Band 9 Samples and How to Win It Thus don't get intimidated if you believe you can't write such essays or speak the exact same way. Examine the model essay and read the comments. Attempt to obtain a notion of the topic. There haven't been any considerable changes to IELTS essay topics in the past several years. The Most Popular Ielts Essay Writing Band 9 Samples Smoking is banned in some specific places so mobi le phone ought to be banned like smoking. Today it is nearly not possible to see human environment without animals. Some people feel it is wrong to continue to keep animals in zoos, while some feel that zoos are both entertaining and ecologically important. Ielts Essay Writing Band 9 Samples Features Thus, the expression, marry for money appears to be appropriate, in a point, at least. Some believe that folks want to live simpler lives to fix environmental issues. Also, certain sorts of information in the incorrect hands can be devastating for society. Some people think that the very best way to lessen the crime is educating people in prison in order that they can receive a job after leaving prison. There is a broad variety of quite natural vocabulary necessary to spell out a graph and there aren't any spelling mistakes. Your writing also needs to be very simple to read and all elements of it are managed properly as a way to guarantee Coherence and Cohesion. You ought to use words that aren't typical in an everyday conversation. There'll be many more words than gaps.

Wednesday, January 1, 2020

The Domestic Impact Of The Vietnam War - 2477 Words

What was the domestic impact of the Vietnam War? The Cold War era proxy war known as the Vietnam War wrecked global havoc during 1955-1975. Although the destruction on the ground occurred in Vietnam, Cambodia and Laos, the bloodshed of the war was just one part of a much larger worldwide communism versus capitalism battle headed by the United States and the Soviet Union. For the U.S., diplomatic and military policies had never before been so tightly intertwined with domestic policies. The war in Vietnam had such an impact on the home front in America that the term, â€Å"The Vietnam Syndrome† is still repeated to this day. The war, which is sometimes seen as a part of the larger anti-communist policy of ‘containment’, is largely to blame for the near destruction of three presidencies, as well as causing numerous political and social divides, a detrimental effect on the U.S. economy, and a credibility gap that caused distrust between government and the people. The focus on the war meant that many domestic issues such as the civil rights movement, the war on poverty, and Johnson’s ideology of the ‘Great Society’, were neglected by the government and therefore limited in their progress. The overall domestic impact of the war in Vietnam was largely negative and extremely divisive. The Vietnam War loomed predominantly over three U.S. presidencies. When John F. Kennedy came to the presidency, he immediately inherited Dwight Eisenhower’s commitment to assist Saigon in its struggleShow MoreRelatedDomestic Political State Of The Nation, Technological Advances, And Doctrinal Changes1511 Words   |  7 PagesThe Evolution of the Cost of War Analyzed through the Domestic Political State of the Nation, Technological Advances, and Doctrinal Changes Politics can be defined as the practice of influencing people through the exercise of power. The main way to control a person or a group of people is to control their finances. 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A lifestyleRead MoreLife From Active Duty Is Notoriously Difficult For Soldiers Suffering From Posttraumatic Stress Disorder1655 Words   |  7 Pagesfigure is based on reports from clinicians and academic research, mainly from the US. â€Å"The small amount of research does suggest that there is a link,† said Professor Forbes. â€Å"It’s obviously not as though everybody with PTSD necessarily engages in domestic violence or partner violence, but it does increase the risk.† That risk increases further for those who sustained PTSD through military service. According to the Department of Veterans’ Affairs, around five-to-20 per cent of veterans will experienceRead MoreThe Containment Policy Was Aimed At Ending The Spread Of Communism1595 Words   |  7 Pagesafter the Soviet Union made several attempts to stretch to Africa, China, Korea, Vietnam and Eastern Europe. How the restriction made it impossible for nations to be seen as distinct, with varying histories, cultures and predicaments. 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Anyone could join this front as long as they opposed Ngo Dinh Diem and wanted to unify Vietnam.The character of the NLF and its relationship to the CommunistsRead MoreVietnam War : A Side Of View988 Words   |  4 Pages Vietnam War: Another Side of View Growing up in the late 1980s in Vietnam, I was getting a more comfortable life than my parents when the economy of Vietnam was on the way of recovery after the Vietnam War. I did not know much about Vietnam War and what my grandparents and my parents had witnessed and experienced. When I was in Vietnam, I have been told repeatedly that it was a 20-year-Resistance-War against America from 1954 to 1975 between the government of South Vietnam and North Vietnam. My